DNA Fragmentation Test in UAE – Advanced Sperm DNA Testing

Facing Unexplained Infertility or Failed IVF?

If you’ve experienced repeated IVF or ICSI failures, unexplained infertility, or poor embryo quality, the cause may lie deeper than routine semen analysis can detect. Many men across Dubai, Abu Dhabi, Sharjah, or anywhere in the UAE face fertility challenges due to sperm DNA fragmentation—a hidden factor that standard tests often miss.

At VIVILITY Fertility Clinic, we offer advanced sperm DNA fragmentation testing in the UAE, helping you uncover subtle but crucial genetic damage that affects your chances of successful conception. With cutting-edge diagnostics and expert consultation, we bring clarity to your fertility journey and offer personalized treatment solutions.

Understanding Sperm DNA Fragmentation and Its Role in Male Fertility

A DNA fragmentation test evaluates the integrity of genetic material in sperm cells. While sperm count and motility are important, the quality of the sperm’s DNA (genetic code) is equally vital for fertilization, embryo development, and pregnancy success.

Sperm DNA fragmentation is measured using the DNA Fragmentation Index (DFI), which indicates the percentage of sperm with damaged DNA strands. High DFI levels have been linked to low fertilization rates, embryo arrest, and recurrent miscarriage.

This test goes beyond routine semen analysis and examines chromatin structure, oxidative stress damage, and genetic viability, offering a deeper understanding of male reproductive health.

The Link Between DNA Damage and Male Infertility Explained

Sperm DNA carries half the genetic material required for a healthy embryo. If that DNA is damaged or fragmented, even a high sperm count may not result in successful fertilization or pregnancy.

Research shows strong associations between DNA fragmentation and:

• Low fertilization rates
• Poor embryo development
• Repeated IVF or ICSI failure
• Recurrent miscarriage
• Reduced implantation rates
• Increased risk of genetic disorders

Understanding the genetic quality of sperm helps in identifying the actual barrier to conception and selecting more effective treatment approaches.

Indications That You May Need Sperm DNA Testing

While not part of the initial fertility test panel, sperm DNA testing is recommended in several scenarios:

• Previous failed IVF or ICSI cycles
• Unexplained infertility, where standard tests show normal results
• Recurrent pregnancy loss or miscarriage
• Advanced paternal age
• History of exposure to environmental toxins, radiation, or heat
• Lifestyle factors such as smoking, stress, obesity, or poor diet
• Diagnosed varicocele
• Poor semen parameters (motility, morphology, count)

In such cases, identifying sperm DNA integrity becomes critical to improving your chances of conception.

Different Testing Methods Used for Assessing Sperm DNA Quality

At VIVILITY, we offer various scientifically validated DNA fragmentation tests that provide accurate insights into sperm health:

• SCSA (Sperm Chromatin Structure Assay): Measures DNA susceptibility to denaturation and quantifies DFI.
• TUNEL Assay: Identifies and quantifies actual DNA strand breaks in individual sperm cells.
• Comet Assay: Provides detailed data on single-strand and double-strand DNA breaks.
• SCD Test (Sperm Chromatin Dispersion Test): Evaluates chromatin integrity through microscopic analysis.

Each method serves a specific purpose, and the choice of test depends on your condition, history, and treatment goals.

Step-by-Step Process of Sperm DNA Testing at VIVILITY

The testing process is simple, accurate, and handled with complete confidentiality at VIVILITY Fertility Clinic:

1. Sample Collection: A semen sample is collected either onsite or at home (with quick lab submission).
2. Semen Preparation: The sample is processed and prepared for molecular analysis.
3. Laboratory Testing: DNA fragmentation is measured using advanced techniques such as SCSA or TUNEL.
4. Result Analysis: The DFI score is calculated, indicating the percentage of sperm with DNA damage.
5. Consultation: Our fertility specialists explain the results in detail and guide the next steps.

The entire test takes just a few hours, with results usually available within 48 to 72 hours.

Interpreting Your DNA Fragmentation Index (DFI) and Fertility Outcomes

The DNA Fragmentation Index (DFI) is a key measure of your sperm’s genetic quality.

• DFI < 15%: Low DNA damage; good fertility potential
• DFI 15–30%: Moderate DNA damage; reduced conception probability
• DFI > 30%: High DNA fragmentation; higher risk of failed IVF/ICSI or miscarriage

Your treatment pathway will be guided by your DFI results. Our specialists use these insights to suggest options like antioxidant therapy, lifestyle changes, or advanced sperm selection techniques during ART procedures.

What Comes After the DNA Fragmentation Test?

Once your test results are reviewed, we help you move forward with a personalized fertility enhancement plan, which may include:

• Lifestyle modification to reduce oxidative stress
• Antioxidant therapy to improve sperm DNA integrity
• PICSI or IMSI techniques for selecting genetically healthier sperm
• ICSI using DNA-screened sperm for better embryo quality
• Varicocele treatment if identified as a cause
• Repeat testing after therapy to assess improvement

Our goal is to ensure you receive the most effective, science-backed treatment strategy.

Accurate Diagnosis Backed by UAE’s Leading Fertility Team

At VIVILITY, you get access to one of the most advanced fertility diagnostic programs in the region. We combine clinical expertise, world-class lab infrastructure, and a patient-focused approach.

Why VIVILITY is trusted across UAE:

• Leading fertility experts and andrologists
• Specialized reproductive diagnostic labs in Dubai and Abu Dhabi
• Personalized care plans tailored to each patient
• Comprehensive support from testing to treatment
• Proven protocols delivering better fertility outcomes

Improving Fertility Outcomes with Precision Diagnostics

With targeted treatment based on DNA fragmentation test results, many patients report remarkable improvements in:

• Pregnancy success rates
• Embryo quality and implantation success
• Reduced miscarriage rates
• Higher IVF and ICSI success
• Better treatment response and fewer ART cycles

Precision diagnostics not only improve results—they reduce the emotional and financial burden of prolonged fertility treatment.

Affordable and Transparent Pricing for Advanced Fertility Testing

We offer cost-effective DNA fragmentation test packages in UAE without compromising accuracy or quality.

• Transparent pricing for SCSA, TUNEL, and other tests
• Flexible male fertility test packages including hormonal and semen analysis
• Competitive rates in Dubai, Abu Dhabi, Sharjah, and other cities
• No hidden costs or additional lab charges
• Affordable options for repeat testing and follow-up

Speak with our team to get a personalized cost estimate based on your diagnostic needs.

Take Control of Your Fertility – Schedule Your Advanced Sperm DNA Test with VIVILITY

Your fertility journey deserves clarity and expert support. At VIVILITY, we help you identify hidden challenges and offer personalized solutions that truly work.

Book your DNA fragmentation test today and get answers that make a difference. Speak to our team of fertility experts, schedule your evaluation, and take the next step toward parenthood with confidence.